Multilocular Cystic Renal Cell Carcinoma

Objective: Multilocular cystic renal cell carcinoma appears to be uncommon subtype of renal cell carcinoma with characteristic gross and microscopic features. This study reports the presentation, diagnosis, and treatment of multilocular cystic renal cell carcinoma, which is a rare entity and its true incidence and biologic behavior are not well known in Jordan. Methods: We have identified two cases of multilocular cystic renal cell carcinoma at Queen Rania Urology Center over the last three years. The clinical, radiological, and pathological features were described and the surgical procedure and follow up outcome were studied. Results: The tumor was an incidental finding in both cases. Ultrasound and computerized tomography (CT) scans were performed prior to surgery but could not identify the tumor. Nephrectomy was performed in both cases. Tumor size was 5 cm in one case and 7 centimeters (cm) in the second. Both cases were followed until the present time and last ultrasound and CT scan proved to be negative for recurrence. Conclusion: Multilocular cystic renal cell carcinoma is uncommon subtype of renal cell carcinoma, and it has a benign clinical course. Nephrectomy is a curative procedure and there is no need for any other adjuvant therapy. The Multilocular renal cell carcinoma must be distinguished from renal cell carcinoma with cystic degeneration and multilocular cystic nephroma.